成人免费网站在线 I 亚洲经典视频在线观看 I 亚洲91精品 I 人人91 I 亚洲黄色短视频 I 国产成人无码av I 女性高潮视频 I 色女综合 I 性欧美69 I 欧美国产日韩在线观看成人 I 亚洲精品第五页 I 欧美另类videosbestsex日本 I 色综合激情网 I 冲田杏梨av I 男女操网站 I 日韩久久一区二区三区 I 91在线视频精品 I 北条麻妃在线一区 I 成色视频 I 亚洲熟女乱综合一区二区 I 欧亚一区二区三区 I 青青在线视频一区二区三区 I 精品国产一区二区亚洲人成毛片 I 成人久久18免费网站漫画 I 国产69精品久久久久777 I 亚洲色大网站www永久网站 I 国产欧美一区二区三区不卡高清 I 国产影片中文字幕 I 性感美女福利视频网站 I 精品久久久久久久久妇女 I 久久成人网站亚洲综合 I 天天操天天天 I 亚洲高清最新av网站 I 奇米影视亚洲狠狠色 I 丝袜美腿美女一区二区 I 欧美日韩一区二区三区在线观看免费 I 日本高清色www在线安全 I 久久人人做人人妻人人玩精品hd I 午夜少妇在线观看视频

RD Recombinant human IL-17A人白介17因子

DESCRIPTION
Source E. coliderived
Thr22Ala158
Accession # Q62386.1
Nterminal
Sequence
Analysis
Thr22
Structure / Form Disulfidelinked
homodimer
Predicted Molecular
Mass
15.5 kDa （monomer）
SPECIFICATIONS
Activity Measured by its ability to induce IL6
secretion by NIH-3T3 mouse embryonic fibroblast cells. Yao, Z. et al. （1995） Immunity 3:811.
The ED50 for this effect is typically 0.251.25
ng/mL.
Endotoxin Level <1.0 EU per 1 μg of the protein by the LAL method.
Purity >97%, by SDSPAGE
under reducing conditions and visualized by silver stain.
Formulation Lyophilized from a 0.2 μm filtered solution in Acetonitrile and TFA with BSA as a carrier protein. See Certificate of Analysis for details.
PREPARATION AND STORAGE
Reconstitution Reconstitute at 25 μg/mL in sterile 4 mM HCl containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediay at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freezethaw
cycles.
l 12 months from date of receipt, 20
to 70
°C as supplied.
l 1 month, 2 to 8 °C under sterile conditions after reconstitution.
l 3 months, 20
to 70
°C under sterile conditions after reconstitution.
BACKGROUND
Interleukin 17 （also known as CTLA8）
is a T cellexpressed
pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of
herpesvirus Saimiri. cDNA clones encoding IL17
have been isolated from activated rat, mouse and human T cells. Mouse IL17
cDNA encodes a 158 amino acid （aa）
residue precursor protein with a 21 amino acid residue signal peptide that is cleaved to yield the 137 aa residue mature IL17.
Both recombinant and natural IL17
have
been shown to exist as disulfide linked homodimers. At the amino acid level, mIL17
shows 57% and 87% sequence identity with herpesvirus and rat IL17,
respectively. An IL17
specific mouse cell surface receptor （IL17
R） has been cloned. While the expression of IL17
mRNA is restricted to activated alpha beta
TCR+CD4CD8T
cells, the expression of mIL17
R mRNA has been detected in virtually all cells and tissues tested. IL17
exhibits multiple biological activities on a
variety of cells including: the induction of IL6
and IL8
production in fibroblasts? the enhancement of surface expression of ICAM1
in fibroblasts? activation of NFκB
and costimulation of T cell proliferation.
References:
1. Kennedy, J. et al., （1996） J. Interferon Cytokine Res. 16:611.
2. Yao, Z. et al., （1995） J. Immunol. 155:5483.
3. Yao, Z. et al., （1995） Immunity 3:811.
4. Rouvier, E. et al., （1993） J. Immunol. 150:5445.

RD Recombinant human IL-17A人白介17因子 詳細產品信息可和選購

上海力敏實業(yè)有限公司代理R&D產品，歡迎
上海力敏實業(yè)有限公司代理R&D產品，歡迎